Research Progress on lncRNA Functions and Mechanisms in Pituitary Adenomas

被引:7
作者
Du, Qiu [1 ,2 ]
Yao, De-Shan [3 ]
Wang, You-Wei [1 ]
Cheng, Cheng [1 ]
机构
[1] Yangzhou Univ, Affiliated Hosp, Dept Neurosurg, 368 Hanjiang Middle Rd, Yangzhou 22500, Jiangsu, Peoples R China
[2] Yangzhou Univ, Affiliated Hosp, Cent Lab, Yangzhou, Jiangsu, Peoples R China
[3] Yangzhou Univ, Affiliated Hosp, Dept Cardiol, Yangzhou, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
pituitary adenomas; long non-coding RNA; mechanism of action; biological function; LONG NONCODING RNA; MALAT1 PROMOTES PROLIFERATION; SQUAMOUS-CELL CARCINOMA; BREAST-CANCER GROWTH; POOR-PROGNOSIS; UP-REGULATION; GENE-EXPRESSION; SNHG1; PREDICTS; FEEDBACK LOOP; MEG3;
D O I
10.1055/a-1142-8815
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite being the most common human neuroendocrine tumor, the pathogenesis of pituitary adenomas (PAs) is still unclear. Long non-coding RNA (lncRNA) is involved in a variety of physiological and pathological processes, and has been shown to play a key role in the process of tumor instigation and development by affecting the proliferation, migration, invasiveness, and metastasis of tumor cells. Therefore, lncRNAs may be used as diagnostic and prognostic markers of tumors. In this paper, the effect of lncRNA on the onset and progression of PAs is reviewed so as to provide a profound understanding of its pathogenesis and clinical reference for the early diagnosis of PAs.
引用
收藏
页码:280 / 288
页数:9
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