Study of interactions between hyaluronan and cationic surfactants by means of calorimetry, turbidimetry, potentiometry and conductometry

被引:12
作者
Krouska, J. [1 ]
Pekar, M. [1 ]
Klucakova, M. [1 ]
Sarac, B. [2 ]
Bester-Rogac, M. [2 ]
机构
[1] Brno Univ Technol, Fac Chem, Mat Res Ctr, Purkynova 118, Brno 61200, Czech Republic
[2] Univ Ljubljana, Fac Chem & Chem Technol, Vecna Pot 113, Ljubljana 1000, Slovenia
关键词
Hyaluronan; Surfactants; Polyelectrolyte-surfactant interactions; CTAB; TFAB; ISOTHERMAL TITRATION CALORIMETRY; TETRADECYLTRIMETHYLAMMONIUM BROMIDE; ANIONIC POLYELECTROLYTE; SODIUM HYALURONATE; AQUEOUS-SOLUTIONS; PHASE-BEHAVIOR; SYSTEMS; ACID; DERIVATIVES; DELIVERY;
D O I
10.1016/j.carbpol.2016.11.069
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The thermodynamics of the micelle formation of the cationic surfactants tetradecyltrimethylammonium bromide (TTAB) and cetyltrimethylammonium bromide (CTAB) with and without the addition of hyaluronan of two molecular weights was studied in aqueous solution by titration calorimetry. Macroscopic phase separation, which was detected by calorimetry and also by conductometry, occurs when charges on the surfactant and hyaluronan are balanced. In contrast, turbidimetry and potentiometry showed hyaluronan-surfactant interactions at very low surfactant concentrations. The observed differences between systems prepared with CTAB and TrAB indicate that besides the electrostatic interactions, which probably predominate, hydrophobic effects also play a significant role in hyaluronan interactions with cationic surfactants. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1837 / 1843
页数:7
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