Nanomaterial-based fluorescent probes for live-cell imaging

被引:45
作者
Li, Qing [1 ]
Liu, Lin [1 ]
Liu, Jin-Wen [1 ]
Jiang, Jian-Hui [1 ]
Yu, Ru-Qin [1 ]
Chu, Xia [1 ]
机构
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo BioSensing & Chemometr, Changsha 410082, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
Fluorescent imaging; Fluorescent probe; Intracellular detection; Intracellular nanosensor; Live-cell imaging; Nanobiosensor; Nanomaterial; Nanosensor; Sensor design; Transduction; GRAPHENE QUANTUM DOTS; RESPONSIVE POLYMERIC NANOPARTICLES; MESSENGER-RNA DETECTION; CARBON DOTS; SILICON NANOPARTICLES; SILVER NANOCLUSTERS; GOLD NANOPARTICLES; ENERGY-TRANSFER; LABEL-FREE; DELIVERY;
D O I
10.1016/j.trac.2014.03.007
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Nanomaterial-based fluorescent probes represent a significant approach to intracellular detection with high spatiotemporal resolution. We review the properties of various nanomaterials that can be used for intracellular nanosensors in terms of the sensor design and the approaches to delivery of nanosensors based on engineering their surfaces. We also review general strategies for these nanosensors based on the transduction mechanisms of the fluorescence signal. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:130 / 144
页数:15
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