Plasma free reversible and irreversible microfluidic bonding

被引：22

作者：

Chu, M. ^{[1
]}

Nguyen, T. T. ^{[2
]}

Lee, E. K. ^{[1
]}

Morival, J. L. ^{[1
]}

Khine, M. ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Biomed Engn, Irvine, CA 92697 USA

[2] Univ Calif Irvine, Dept Chem Engn, Irvine, CA 92697 USA

来源：

LAB ON A CHIP | 2017年 / 17卷 / 02期

基金：

美国国家科学基金会;

关键词：

CELL-CULTURE; DEVICES; POLY(DIMETHYLSILOXANE); POLYDIMETHYLSILOXANE; CHIPS; ATTACHMENT; CHANNELS; FLOW;

D O I：

10.1039/c6lc01338d

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate a facile, plasma free process to fabricate both reversibly and irreversibly sealed microfluidic chips using a PDMS-based adhesive polymer mixture. This is a versatile method that is compatible with current PDMS microfluidics processes. It allows for easier fabrication of multilayer microfluidic devices and is compatible with micropatterning of proteins for cell culturing. When combined with our ShrinkyDink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom.

引用

页码：267 / 273

页数：7

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