State of the art in oncology: High risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and POST-TEXT 3 and 4 hepatoblastoma

被引:15
作者
La Quaglia, Michael P. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA
关键词
Neuroblastoma; Alveolar rhabdomyosarcoma; Desmoplastic small round cell tumor; Hepatoblastoma; STAGE-III NEUROBLASTOMA; COMPLETE SURGICAL RESECTION; BONE-MARROW-TRANSPLANTATION; GROSS TOTAL RESECTION; LIVER-TRANSPLANTATION; MULTIMODAL TREATMENT; PROLONGS SURVIVAL; IV NEUROBLASTOMA; SURGERY; CHILDREN;
D O I
10.1016/j.jpedsurg.2013.11.029
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Despite advances in the treatment of pediatric cancers during the past few decades, high-risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and hepatoblastomas with 3 or 4 sector involvement after chemotherapy continue to present significant challenges. This review summarizes recent research on the management of these diseases, with a special focus on the use of surgical debulking, genetic analysis, immunotherapy, and chemotherapy in improving outcomes of patients with these solid tumors. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:233 / 240
页数:8
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