Parsing the Heterogeneity and Increasing Specificity: A Commentary on "Neurocognitive Functioning in Bipolar Disorder"

被引:0
作者
Frazier, Thomas W. [1 ,2 ]
机构
[1] Cleveland Clin CRS10, Ctr Pediat Behav Hlth, Inst Pediat, Cleveland, OH 44104 USA
[2] Cleveland Clin CRS10, Ctr Autism, Inst Pediat, Cleveland, OH 44104 USA
关键词
bipolar disorder; heterogeneity; neurocognitive functioning; specificity; EUTHYMIC PATIENTS; DEFICITS; ENDOPHENOTYPE; PERFORMANCE; ATTENTION; REWARD;
D O I
10.1111/j.1468-2850.2009.01163.x
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
"Neurocognitive Functioning in Bipolar Disorder" is a comprehensive examination of the literatures examining neurocognitive and neuroimaging studies in pediatric and adult bipolar disorder. Based upon this review, the present commentary highlights four important areas of future investigation: increasing specificity of cognitive measures, evaluating the specificity of neurocognitive abnormalities to bipolar disorder, modeling heterogeneity of neurocognitive functioning within bipolar disorder, and searching for core neurocognitive processes more closely linked to the dysfunctional behavior seen in bipolar disorder. In addition to greater phenotypic clarity, attention to these four areas will be crucial for advancing the field. The present commentary provides recommendations for addressing these areas to facilitate progress in neurocognitive and neurobiological research of bipolar disorder.
引用
收藏
页码:251 / 255
页数:5
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