Ru-catalyzed ortho-oxidative alkenylation of 2-arylbenzo[d]thiazoles in aqueous solution of anionic surfactant sodium dodecylbenzenesulfonate (SDBS)

被引：15

作者：

Ping, Yuanyuan

Chen, Zhaobin

Ding, Qiuping ^{[1
]}

Zheng, Qiang

Lin, Yuqing

Peng, Yiyuan

机构：

[1] Jiangxi Normal Univ, Key Lab Small Funct Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China

来源：

TETRAHEDRON | 2017年 / 73卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Alkenylation; C-H functionalization; 2-arylbenzo[d]thiazoles; 2-arylthiazoles; Aqueous; C-H ALKENYLATION; CARBON-CARBON BOND; ORTHO-OLEFINATION; DIRECTING GROUPS; ORGANIC-REACTIONS; ANTITUMOR BENZOTHIAZOLES; 2-SUBSTITUTED AZAARENES; BIOLOGICAL-PROPERTIES; DIRECT C2-OLEFINATION; EXPEDIENT SYNTHESIS;

D O I：

10.1016/j.tet.2016.12.050

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild and efficient Ru-catalyzed ortho-oxidative alkenylation of 2-arylbenzo[d]thiazoles through twofold C-H bond functionalization in aqueous solution of anionic surfactant sodium dodecylbenzenesulfonate (SDBS) has been developed using activated olefins as coupling partner. The protocol could be carried out smoothly on a gram scale, recyclable, and applicable to 2-arylthiazoles. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：594 / 603

页数：10