Immunocompromised and immunocompetent mouse models for head and neck squamous cell carcinoma

被引：35
作者：
Lei, Zhen-ge [1 ]
Ren, Xiao-hua [2 ,3 ]
Wang, Sha-sha [4 ]
Liang, Xin-hua [4 ,5 ]
Tang, Ya-ling [4 ,6 ]
机构：
[1] Nanchang Univ, Stomatol Hosp, Dept Oral & Maxillofacial Surg, Nanchang, Jiangxi, Peoples R China
[2] Sichuan Med Sci Acad, Dept Stomatol, Chengdu, Sichuan, Peoples R China
[3] Sichuan Prov Peoples Hosp, Chengdu, Sichuan, Peoples R China
[4] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, 14,Sect 3,Renminnan Rd, Chengdu 610041, Sichuan, Peoples R China
[5] Sichuan Univ, West China Coll Stomatol, Dept Oral & Maxillofacial Surg, 14,Sect 3,Renminnan Rd, Chengdu 610041, Sichuan, Peoples R China
[6] Sichuan Univ, West China Hosp Stomatol, Dept Oral Pathol, Chengdu 610041, Sichuan, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2016年 / 9卷
基金：
中国国家自然科学基金;
关键词：
head and neck squamous cell carcinoma; HNSCC; mouse models; immunocompromised models; immunocompetent models; transgenic models; PAPILLOMAVIRUS TYPE-16 E6; UPPER AERODIGESTIVE TRACT; GROWTH-FACTOR RECEPTOR; CANCER STEM-CELLS; TRANSGENIC MICE; MURINE MODEL; ORAL-CAVITY; IN-VITRO; ANIMAL-MODELS; K-RAS;
D O I：
10.2147/OTT.S95633
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Mouse models can closely mimic human oral squamous epithelial carcinogenesis, greatly expand the in vivo research possibilities, and play a critical role in the development of diagnosis, monitoring, and treatment of head and neck squamous cell carcinoma. With the development of the recent research on the contribution of immunity/inflammation to cancer initiation and progression, mouse models have been divided into two categories, namely, immunocompromised and immunocompetent mouse models. And thus, this paper will review these two kinds of models applied in head and neck squamous cell carcinoma to provide a platform to understand the complicated histological, molecular, and genetic changes of oral squamous epithelial tumorigenesis.
引用
收藏
页码：545 / 555
页数：11
相关论文
共 141 条
[71]   Effect of local hyperthermia on lymphangiogenic factors VEGF-C and -D in a nude mouse xenograft model of tongue squamous cell carcinoma [J].
Liang, Xinhua ;
Zhou, Hao ;
Liu, Xian ;
He, Yongwen ;
Tang, Yaling ;
Zhu, Guiquan ;
Zheng, Min ;
Yang, Jing .
ORAL ONCOLOGY, 2010, 46 (02) :111-115
[72]   Therapeutic Efficacy Evaluation of Curcumin on Human Oral Squamous Cell Carcinoma Xenograft Using Multimodalities of Molecular Imaging [J].
Lin, Yu-Chuan ;
Chen, Hong-Wen ;
Kuo, Yu-Cheng ;
Chang, Ya-Fang ;
Lee, Yi-Jang ;
Hwang, Jeng-Jong .
AMERICAN JOURNAL OF CHINESE MEDICINE, 2010, 38 (02) :343-358
[73]   Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice [J].
Liu, Limin ;
Tang, Xiao-Han ;
Scognamiglio, Theresa ;
Gudas, Lorraine J. .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2010, 21 (10) :975-982
[74]  
Liu X, 1999, Zhonghua Kou Qiang Yi Xue Za Zhi, V34, P354
[75]   The tumor microenvironment and its contribution to tumor evolution toward metastasis [J].
Lorusso, Girieca ;
Ruegg, Curzio .
HISTOCHEMISTRY AND CELL BIOLOGY, 2008, 130 (06) :1091-1103
[76]   Mouse models for human head and neck squamous cell carcinomas [J].
Lu, Shi-Long ;
Herrington, Heather ;
Wang, Xiao-Jing .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2006, 28 (10) :945-954
[77]  
Macchiarini Francesca, 2005, J Exp Med, V202, P1307, DOI 10.1084/jem.20051547
[78]   COMPARISON OF EPITHELIAL DYSPLASIA IN HAMSTER-CHEEK POUCH CARCINOGENESIS AND HUMAN ORAL-MUCOSA [J].
MACDONALD, DG .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1981, 10 (03) :186-191
[79]   Cancer-related inflammation [J].
Mantovani, Alberto ;
Allavena, Paola ;
Sica, Antonio ;
Balkwill, Frances .
NATURE, 2008, 454 (7203) :436-444
[80]   A novel rasH2 mouse carcinogenesis model that is highly susceptible to 4-NQO-induced tongue and esophageal carcinogenesis is useful for preclinical chemoprevention studies [J].
Miyamoto, Shingo ;
Yasui, Yumiko ;
Kim, Mihye ;
Sugie, Shigeyuki ;
Murakami, Akira ;
Ishigamori-Suzuki, Rikako ;
Tanaka, Takuji .
CARCINOGENESIS, 2008, 29 (02) :418-426
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