A chemical concept for the treatment of Tay-Sachs disease

被引：30

作者：

Kolter, T

机构：

[1] Inst. F. Org. Chem. Und Biochem. D., D-53121 Bonn

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1997年 / 36卷 / 18期

关键词：

bioorganic; chemistry; enzymes; glycolipids; inhibitors; sphingolipids;

D O I：

10.1002/anie.199719551

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1955 / 1959

页数：5

共 21 条

[1]

AIGNER A, 1997, ANGEW CHEM, V109, P24

[2]

Aigner A., 1997, Angew. Chem., V36, P24

[3]

FISCHL MA, 1994, J ACQ IMMUN DEF SYND, V7, P139

[4] LYSOSOMAL STORAGE DISEASES [J].

GIESELMANN, V .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1995, 1270 (2-3) :103-136

[5] FUNCTIONAL-ROLE OF GLYCOSPHINGOLIPIDS IN CELL RECOGNITION AND SIGNALING [J].

HAKOMORI, S ;

IGARASHI, Y .

JOURNAL OF BIOCHEMISTRY, 1995, 118 (06) :1091-1103

[6]

Ichikawa S, 1996, P NATL ACAD SCI USA, V93, P4638, DOI 10.1073/pnas.93.10.4638

[7] Inhibitors of glycosphingolipid biosynthesis [J].

Kolter, T ;

Sandhoff, K .

CHEMICAL SOCIETY REVIEWS, 1996, 25 (06) :371-&

[8] QUANTITATIVE CORRELATION BETWEEN THE RESIDUAL ACTIVITY OF BETA-HEXOSAMINIDASE-A AND ARYLSULFATASE-A AND THE SEVERITY OF THE RESULTING LYSOSOMAL STORAGE DISEASE [J].

LEINEKUGEL, P ;

MICHEL, S ;

CONZELMANN, E ;

SANDHOFF, K .

HUMAN GENETICS, 1992, 88 (05) :513-523

[9] Purification and characterization of UDPP-glucose:ceramide glucosyltransferase from rat liver Golgi membranes [J].

Paul, P ;

Kamisaka, Y ;

Marks, DL ;

Pagano, RE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (04) :2287-2293

[10] INHIBITORS OF GLYCOSPHINGOLIPID BIOSYNTHESIS [J].

PLATT, FM ;

BUTTERS, TD .

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, 1995, 7 (38) :495-511

← 1 2 3 →