Lung Cancer in Never-Smoking Women: A Sub-Analysis of the Spanish Female-Specific Database WORLD07

被引:12
作者
Vinolas, Nuria [1 ]
Garrido, Pilar [2 ]
Isla, Dolores [3 ]
Provencio, Mariano [4 ]
Majem, Margarita [5 ]
Artal, Angel [6 ]
Carcereny, Enric [7 ]
Garcia Campelo, Rosario [8 ]
Lianes, Pilar [9 ]
De la Penas, Ramon [10 ]
Felip, Enriqueta [11 ]
机构
[1] Hosp Clin Barcelona, Villarroel 170, E-08036 Barcelona, Spain
[2] Hosp Univ Ramon y Cajal, Madrid, Spain
[3] Hosp Clin Lozano Blesa, Zaragoza, Spain
[4] Hosp Univ Puerta de Hierro Majadahonda, Madrid, Spain
[5] Hosp Santa Creu & Sant Pau, Barcelona, Spain
[6] Hosp Miguel Servet, Zaragoza, Spain
[7] Hosp Badalona Germans Trias & Pujol, Barcelona, Spain
[8] Complejo Hosp Univ A Coruna, Coruna, Spain
[9] Hosp Mataro, Consorci Sanitari Maresme, Barcelona, Spain
[10] Hosp Prov Castellon, Castellon De La Plana, Spain
[11] Hosp Valle De Hebron, Barcelona, Spain
关键词
Lung cancer; prognostic factors; Spanish women; never smokers; smoking; SMOKERS; RISK; EPIDEMIOLOGY; COUNTRIES; HISTOLOGY; SURVIVAL; PATTERNS; GENDER; TRENDS;
D O I
10.1080/07357907.2017.1295461
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The WORLD07 study characterizes lung cancer in Spanish women. This analysis investigated lung cancer features in never-smoking women. Of 2072 women recruited, 2035 were analyzed. Patient characteristics and demographics were similar for current/former smokers and never smokers. Among never smokers, 38.3% were exposed to passive smoking. Non-small-cell lung cancer was the most common type (78.8% of current/former smokers and 96.1% of never smokers) and adenocarcinoma the most common histology (69.1% and 83.4% respectively). There was a high incidence of lung cancer in Spanish never-smoking women and a high proportion (about 50%) had mutant epidermal growth factor receptor.
引用
收藏
页码:358 / 365
页数:8
相关论文
共 29 条
[1]   Invited Commentary: The Etiology of Lung Cancer in Men Compared With Women [J].
Alberg, Anthony J. ;
Wallace, Kristin ;
Silvestri, Gerard A. ;
Brock, Malcolm V. .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2013, 177 (07) :613-616
[2]  
[Anonymous], J NATL CANC I
[3]   Lung cancer mortality trends in 36 European countries: secular trends and birth cohort patterns by sex and region 1970-2007 [J].
Bray, Freddie Ian ;
Weiderpass, Elisabete .
INTERNATIONAL JOURNAL OF CANCER, 2010, 126 (06) :1454-1466
[4]   Evidence for a genetical contribution to non-smoking-related lung cancer [J].
Carr, Shamus R. ;
Akerley, Wallace ;
Hashibe, Mia ;
Cannon-Albright, Lisa A. .
THORAX, 2015, 70 (11) :1033-1039
[5]   BioCAST/IFCT-1002: epidemiological and molecular features of lung cancer in never-smokers [J].
Couraud, Sebastien ;
Souquet, Pierre-Jean ;
Paris, Christophe ;
Do, Pascal ;
Doubre, Helene ;
Pichon, Eric ;
Dixmier, Adrien ;
Monnet, Isabelle ;
Etienne-Mastroianni, Benedicte ;
Vincent, Michel ;
Tredaniel, Jean ;
Perrichon, Marielle ;
Foucher, Pascal ;
Coudert, Bruno ;
Moro-Sibilot, Denis ;
Dansin, Eric ;
Labonne, Stephanie ;
Missy, Pascale ;
Morin, Franck ;
Blanche, Helene ;
Zalcman, Gerard .
EUROPEAN RESPIRATORY JOURNAL, 2015, 45 (05) :1403-1414
[6]   Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012 [J].
Ferlay, J. ;
Steliarova-Foucher, E. ;
Lortet-Tieulent, J. ;
Rosso, S. ;
Coebergh, J. W. W. ;
Comber, H. ;
Forman, D. ;
Bray, F. .
EUROPEAN JOURNAL OF CANCER, 2013, 49 (06) :1374-1403
[7]   Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 [J].
Ferlay, Jacques ;
Soerjomataram, Isabelle ;
Dikshit, Rajesh ;
Eser, Sultan ;
Mathers, Colin ;
Rebelo, Marise ;
Parkin, Donald Maxwell ;
Forman, David ;
Bray, Freddie .
INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (05) :E359-E386
[8]   Family history of lung cancer in never smokers with non-small-cell lung cancer and its association with tumors harboring EGFR mutations [J].
Gaughan, Elizabeth M. ;
Cryer, Sarah K. ;
Yeap, Beow Y. ;
Jackman, David M. ;
Costa, Daniel B. .
LUNG CANCER, 2013, 79 (03) :193-197
[9]  
Isla D, 2006, ANN ONCOL, V17, P218
[10]   Epidemiology of Lung Cancer in Women: Risk Factors, Survival, and Screening [J].
Kligerman, Seth ;
White, Charles .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2011, 196 (02) :287-295