Histological analysis of calcium phosphate bone grafts for surgically created periodontal bone defects in dogs

被引:25
|
作者
Sugawara, Akiyoshi [1 ,2 ]
Fujikawa, Kenji [2 ,3 ]
Takagi, Shozo [4 ]
Chow, Laurence C. [4 ]
机构
[1] Sugawara Dent Clin, Tokyo, Japan
[2] Nihon Univ, Sch Dent, Tokyo 101, Japan
[3] Fujikawa Dent Off, Tokyo, Japan
[4] NIST, Paffenbarger Res Ctr, Gaithersburg, MD 20899 USA
关键词
Histopathological reaction; Calcium phosphate cement; Periodontal bone defect;
D O I
10.4012/dmj.27.787
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
A calcium phosphate cement (CPC-1), prepared by mixing an equimolar mixture of tetracalcium phosphate and dicalcium phosphate anhydrous with water, has been shown to be highly biocompatible and osteoconductive. A new type of calcium phosphate cement (CPC-2), prepared by mixing a mixture of a-tricalcium phosphate and calcium carbonate with pH 7.4 sodium phosphate solution, was also reported to be highly biocompatible. The objective of the present Study was to compare the osteoconductivities of CPC-1 and CPC-2 when implanted in surgically created defects in the jaw bones of clogs. At, 1 month after surgery, implanted CPC-1 was partially replaced by new bone and converted to bone within 6 months. In comparison, at I month after surgery, the defect filled with CPC-2 was mostly replaced by new bone. Therefore, bone formation in CPC-2-filled pocket was more rapid than in CPC-1-filled pocket. These findings Supported the hypothesis that CPC-2 converted to bone more rapidly than CPC-1.
引用
收藏
页码:787 / 794
页数:8
相关论文
共 50 条
  • [41] FACTORS (MATERIALS) INFLUENCING THE REGENERATION OF ALVEOLAR BONE IN PERIODONTAL DEFECTS IN DOGS
    KIM, CK
    JOURNAL OF DENTAL RESEARCH, 1995, 74 (03) : 988 - 988
  • [42] Bone formation of intrabony defects in beagle dogs using calcium phosphate glass and glass-ceramics
    Choi, SH
    Baik, DH
    Kim, CS
    Kim, CK
    Kim, KN
    Kim, KM
    LeGeros, RZ
    Lee, YK
    BIOCERAMICS 17, 2005, 284-286 : 957 - 960
  • [43] Early new bone formation in ovine intramuscular defects: comparison between different silicate-containing calcium phosphate synthetic bone grafts
    Iain R. Gibson
    Viviana R. Lopes
    Rema Oliver
    Tian Wang
    Dan Wills
    Tom Buckland
    William R. Walsh
    Journal of Orthopaedic Surgery and Research, 20 (1)
  • [44] Autologous bone versus calcium-phosphate ceramics in treatment of experimental bone defects
    Bloemers, FW
    Blokhuis, TJ
    Patka, P
    Bakker, FC
    Wippermann, BW
    Haarman, HJTM
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2003, 66B (02) : 526 - 531
  • [45] Repair of cranial bone defects with calcium phosphate ceramic implant or autogenous bone graft
    da Silva, Rosane Vieira
    Bertran, Celso Aparecido
    Kawachi, Elizabete Yoshie
    Camilli, Jose Angelo
    JOURNAL OF CRANIOFACIAL SURGERY, 2007, 18 (02) : 281 - 286
  • [46] MACROPOROUS CALCIUM-PHOSPHATE CERAMIC FOR LONG-BONE SURGERY IN HUMANS AND DOGS - CLINICAL AND HISTOLOGICAL STUDY
    DACULSI, G
    PASSUTI, N
    MARTIN, S
    DEUDON, C
    LEGEROS, RZ
    RAHER, S
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (03): : 379 - 396
  • [47] Brazilian Research Academy and Scientific Evidence on Calcium Phosphate Bone Grafts
    Rodrigues, Carla Valeria M.
    Fernandes, Ligia L.
    Soares, Gloria D. A.
    BIOCERAMICS 21, 2009, 396-398 : 217 - 220
  • [48] RESTORATION OF LONG BONE DEFECTS WITH MASSIVE BONE GRAFTS
    SCUDERI, C
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1948, 137 (13): : 1116 - 1121
  • [49] Efficacy of Nano Biphasic Calcium Phosphate in the Treatment of Bone Defects
    Qi, Shangfeng
    Wang, Lanlei
    Zhang, Chunxiang
    Li, Jian-Min
    Chen, Yangxi
    Liao, Yunmao
    INTEGRATED FERROELECTRICS, 2011, 129 : 196 - 200
  • [50] Treatment of periodontal defects in dogs using an injectable composite hydrogel/biphasic calcium phosphate
    Struillou, Xavier
    Boutigny, Herve
    Badran, Zahi
    Fellah, Borhane H.
    Gauthier, Olivier
    Sourice, Sophie
    Pilet, Paul
    Rouillon, Thierry
    Layrolle, Pierre
    Weiss, Pierre
    Soueidan, Assem
    JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2011, 22 (07) : 1707 - 1717