Optimizing hematopoietic stem cell engraftment: a novel role for thrombopoietin

被引:8
作者
Verfaillie, CM [1 ]
机构
[1] Univ Minnesota, Sch Med, Dept Med, Div Hematol Oncol & Transplantat,Stem Cell Inst, Minneapolis, MN 55455 USA
关键词
D O I
10.1172/JCI200216376
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
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页码:303 / 304
页数:2
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共 16 条
  • [1] Thrombopoietin and the c-Mpl receptor: insights from gene targeting
    Alexander, WS
    [J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1999, 31 (10) : 1027 - 1035
  • [2] c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia
    Ballmaier, M
    Germeshausen, M
    Schulze, H
    Cherkaoui, K
    Lang, S
    Gaudig, A
    Krukemeier, S
    Eilers, M
    Strauss, G
    Welte, K
    [J]. BLOOD, 2001, 97 (01) : 139 - 146
  • [3] Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor
    Basser, RL
    O'Flaherty, E
    Green, M
    Edmonds, M
    Nichol, J
    Menchaca, DM
    Cohen, B
    Begley, CG
    [J]. BLOOD, 2002, 99 (07) : 2599 - 2602
  • [4] BERNSTEIN A, 1991, SEMIN HEMATOL, V28, P138
  • [5] Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34(+)CD38(-) bone marrow cells with multilineage potential at the single-cell level: Key role of thrombopoietin
    Borge, OJ
    Ramsfjell, V
    Cui, L
    Jacobsen, SEW
    [J]. BLOOD, 1997, 90 (06) : 2282 - 2292
  • [6] Regulation of thrombopoietin levels by c-mpl - Mediated binding to platelets
    Fielder, PJ
    Gurney, AL
    Stefanich, E
    Marian, M
    Moore, MW
    CarverMoore, K
    deSauvage, FJ
    [J]. BLOOD, 1996, 87 (06) : 2154 - 2161
  • [7] Thrombopoietin expands hematopoietic stem cells after transplantation
    Fox, N
    Priestley, G
    Papayannopoulou, T
    Kaushansky, K
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2002, 110 (03) : 389 - 394
  • [8] Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-β2 microglobulin-null mice
    Glimm, H
    Eisterer, W
    Lee, K
    Cashman, J
    Holyoake, TL
    Nicolini, F
    Shultz, LD
    von Kalle, C
    Eaves, CJ
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (02) : 199 - 206
  • [9] PROMOTION OF MEGAKARYOCYTE PROGENITOR EXPANSION AND DIFFERENTIATION BY THE C-MPL LIGAND THROMBOPOIETIN
    KAUSHANSKY, K
    LOK, S
    HOLLY, RD
    BROUDY, VC
    LIN, N
    BAILEY, MC
    FORSTROM, JW
    BUDDLE, MM
    OORT, PJ
    HAGEN, FS
    ROTH, GJ
    PAPAYANNOPOULOU, T
    FOSTER, DC
    [J]. NATURE, 1994, 369 (6481) : 568 - 571
  • [10] TARGETED DISRUPTION OF THE FLK2/FLT3 GENE LEADS TO DEFICIENCIES IN PRIMITIVE HEMATOPOIETIC PROGENITORS
    MACKAREHTSCHIAN, K
    HARDIN, JD
    MOORE, KA
    BOAST, S
    GOFF, SP
    LEMISCHKA, IR
    [J]. IMMUNITY, 1995, 3 (01) : 147 - 161