Photocatalytic aerobic oxidation/semipinacol rearrangement sequence: a concise route to the core of pseudoindoxyl alkaloids

被引：93

作者：

Ding, Wei ^{[1
]}

Zhou, Quan-Quan ^{[1
]}

Xuan, Jun ^{[1
]}

Li, Tian-Ren ^{[1
]}

Lu, Liang-Qiu ^{[1
]}

Xiao, Wen-Jing ^{[1
,2
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China

[2] Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300000, Peoples R China

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 33期

基金：

中国国家自然科学基金;

关键词：

Aerobic oxidation; 2,2-Disubstituted indolin-3-one; Semipinacol rearrangement; Photocatalysis; LIGHT PHOTOREDOX CATALYSIS; C-BOND-CLEAVAGE; VISIBLE-LIGHT; SINGLET-OXYGEN; MOLECULAR-OXYGEN; SYNTHETIC ROUTE; OXIDATION; INDOLES; EFFICIENT; ALDEHYDES;

D O I：

10.1016/j.tetlet.2014.06.102

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A visible light-induced photocatalytic aerobic oxidation/semipinacol rearrangement has been successfully developed. This methodology allows for efficient conversion of a wide range of indoles into the synthetically significant 2,2-disubstituted indolin-3-ones, the core structure of pseudoindoxyl alkaloids, under mild reaction conditions. (C) 2014 Published by Elsevier Ltd.

引用

页码：4648 / 4652

页数：5

共 57 条

[21] Study of the addition of Grignard reagents to 2-aryl-3H-indol-3-ones [J].