Project for the development of the linac based NCT facility in University of Tsukuba

被引:84
作者
Kumada, H. [1 ]
Matsumura, A. [2 ]
Sakurai, H. [1 ]
Sakae, T. [1 ]
Yoshioka, M. [3 ]
Kobayashi, H. [3 ]
Matsumoto, H. [3 ]
Kiyanagi, Y. [4 ]
Shibata, T. [5 ]
Nakashima, H. [5 ]
机构
[1] Univ Tsukuba, Proton Med Res Ctr, Tsukuba, Ibaraki 3058575, Japan
[2] Univ Tsukuba, Dept Neurosurg, Tsukuba, Ibaraki 3058575, Japan
[3] High Energy Accelerator Res Org, Tsukuba, Ibaraki 3050801, Japan
[4] Hokkaido Univ, Lab Quantum Beam Syst, Sapporo, Hokkaido 0600808, Japan
[5] Japan Atom Energy Agcy, J PARC Ctr, Tokai, Ibaraki 3191195, Japan
关键词
Accelerator based neutron source; Accelerator based BNCT; Linac; Beryllium target; Treatment planning system;
D O I
10.1016/j.apradiso.2014.02.018
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A project team headed by University of Tsukuba launched the development of a new accelerator based BNCT facility. In the project, we have adopted Radio-Frequency Quadrupole (RFQ)+Drift Tube Linac (DTL) type linac as proton accelerators. Proton energy generated from the linac was set to 8 MeV and average current was 10 mA. The linac tube has been constructed by Mitsubishi Heavy Industry Co. For neutron generator device, beryllium is selected as neutron target material; high intensity neutrons are generated by the reaction with beryllium and the 80 kW proton beam. Our team chose beryllium as the neutron target material. At present beryllium target system is being designed with Monte-Carlo estimations and heat analysis with ANSYS. The neutron generator consists of moderator, collimator and shielding. It is being designed together with the beryllium target system. We also acquired a building in Tokai village; the building has been renovated for use as BNCT treatment facility. It is noteworthy that the linac tube had been installed in the facility in September 2012. In BNCT procedure, several medical devices are required for BNCT treatment such as treatment planning system, patient positioning device and radiation monitors. Thus these are being developed together with the linac based neutron source. For treatment planning system, we are now developing a new multi-modal Monte-Carlo treatment planning system based on JCDS. The system allows us to perform dose estimation for BNCT as well as particle radiotherapy and X-ray therapy. And the patient positioning device can navigate a patient to irradiation position quickly and properly. Furthermore the device is able to monitor movement of the patient's position during irradiation. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:211 / 215
页数:5
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