Efficacy of Albaconazole against Candida albicans in a Vaginitis Model

被引：14
作者：
Gonzalez, Gloria M. [1 ]
Robledo, Efren
Garza-Gonzalez, Elvira
Elizondo, Mariana
Gerardo Gonzalez, J. [2 ]
机构：
[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Microbiol, Colonia Mitras Ctr, Monterrey 64460, Nuevo Leon, Mexico
[2] Univ Autonoma Nuevo Leon, Fac Med, Univ Hosp, Monterrey 64460, Nuevo Leon, Mexico
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 10期
关键词：
IN-VITRO; UR-9825; FLUCONAZOLE;
D O I：
10.1128/AAC.00565-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The efficacy of albaconazole (ABC) was evaluated using a murine model of vaginal Candida albicans infection. Both ABC and fluconazole (FLC) were effective in reducing the fungal load from vaginas of infected mice; however, ABC demonstrated encouraging activities against an FLC-resistant strain, with trends toward superiority over FLC in some treatment groups.
引用
收藏
页码：4540 / 4541
页数：2
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