Efficacy of Albaconazole against Candida albicans in a Vaginitis Model

被引：14

作者：

Gonzalez, Gloria M. ^{[1
]}

Robledo, Efren

Garza-Gonzalez, Elvira

Elizondo, Mariana

Gerardo Gonzalez, J. ^{[2
]}

机构：

[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Microbiol, Colonia Mitras Ctr, Monterrey 64460, Nuevo Leon, Mexico

[2] Univ Autonoma Nuevo Leon, Fac Med, Univ Hosp, Monterrey 64460, Nuevo Leon, Mexico

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 10期

关键词：

IN-VITRO; UR-9825; FLUCONAZOLE;

D O I：

10.1128/AAC.00565-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The efficacy of albaconazole (ABC) was evaluated using a murine model of vaginal Candida albicans infection. Both ABC and fluconazole (FLC) were effective in reducing the fungal load from vaginas of infected mice; however, ABC demonstrated encouraging activities against an FLC-resistant strain, with trends toward superiority over FLC in some treatment groups.

引用

页码：4540 / 4541

页数：2

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