Pharmacogenomics in the UK National Health Service: opportunities and challenges

被引:17
作者
Turner, Richard M. [1 ]
Newman, William G. [2 ]
Bramon, Elvira [3 ]
McNamee, Christine J. [1 ]
Wong, Wai Lup [4 ]
Misbah, Siraj [5 ]
Hill, Sue [6 ]
Caulfield, Mark [7 ]
Pirmohamed, Munir [1 ]
机构
[1] Univ Liverpool, Dept Pharmacol & Therapeut, Liverpool L69 3GL, Merseyside, England
[2] Manchester Univ NHS Fdn Trust, Manchester Ctr Genom Med, Manchester M13 9WL, Lancs, England
[3] UCL, Div Psychiat, Charles Bell House,67-73 Riding House St, London W1W 7EJ, England
[4] East & North Hertfordshire NHS Trust, Coreys Mill Lane, Stevenage SG1 4AB, Herts, England
[5] John Radcliffe Hosp, Headley Way, Oxford OX3 9DU, England
[6] NHS England, Skipton House,80 London Rd, London SE1 6LH, England
[7] Queen Mary Univ London, William Harvey Res Inst, Charterhouse Sq, London EC1M 6BQ, England
基金
英国工程与自然科学研究理事会; 英国医学研究理事会;
关键词
HYPERSENSITIVITY REACTIONS; CLINICAL IMPLEMENTATION; CONSORTIUM; PROJECT; DESIGN;
D O I
10.2217/pgs-2020-0091
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Despite increasing interest in pharmacogenomics, and the potential benefits to improve patient care, implementation into clinical practice has not been widespread. Recently, there has been a drive to implement genomic medicine into the UK National Health Service (NHS), largely spurred on by the success of the 100,000 Genomes Project. The UK Pharmacogenetics and Stratified Medicine Network, NHS England and Genomics England invited experts from academia, the healthcare sector, industry and patient representatives to come together to discuss the opportunities and challenges of implementing pharmacogenomics into the NHS. This report highlights the discussions of the workshop to provide an overview of the issues that need to be considered to enable pharmacogenomic medicine to become mainstream within the NHS.
引用
收藏
页码:1237 / 1246
页数:10
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