Delivery of short hairpin RNA sequences by using a replication-competent avian retroviral vector

被引：30

作者：

Bromberg-White, JL

Webb, CP

Patacsil, VS

Miranti, CK

Williams, BO

Holmen, SL

机构：

[1] Van Andel Res Inst, Lab Cell Signaling & Carcinogenesis, Grand Rapids, MI 49503 USA

[2] Van Andel Res Inst, Lab Tumor Metastasis & Angiogenesis, Grand Rapids, MI 49503 USA

[3] Van Andel Res Inst, Lab Integrin Signaling & Tumorigenesis, Grand Rapids, MI 49503 USA

来源：

JOURNAL OF VIROLOGY | 2004年 / 78卷 / 09期

关键词：

D O I：

10.1128/JVI.78.9.4914-4916.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.

引用

收藏

页码：4914 / 4916

页数：3

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