Predictors of persistence and remission of ADHD into adolescence: Results from a four-year prospective follow-up study

被引:350
|
作者
Biederman, J
Faraone, S
Milberger, S
Curtis, S
Chen, L
Marrs, A
Ouellete, C
Moore, P
Spencer, T
机构
[1] Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA
[2] Pediatric Psychopharmacology Unit, Massachusetts General Hospital, ACC 725, Boston, MA 02114
来源
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1996年 / 35卷 / 03期
关键词
attention-deficit hyperactivity disorder; persistence; predictors; remission; longitudinal study;
D O I
10.1097/00004583-199603000-00016
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Objective: To evaluate the predictors of persistence and the timing of remission of attention-deficit hyperactivity disorder (ADHD). Method: Subjects were 6- to 17-year old Caucasian, non-Hispanic boys with and without ADHD. DSM-III-R structured diagnostic interviews and blind raters were used to examine psychiatric diagnoses, cognitive achievement, social, school, and family functioning at a 4-year follow-up assessment. Results: At the 4-year follow-up assessment, 85% of children with ADHD continued to have the disorder and 15% remitted. Of those who remitted, half did so in childhood and the other half in adolescence. Predictors of persistence were familiality of ADHD, psychosocial adversity, and comorbidity with conduct, mood, and anxiety disorders. Conclusions: The findings prospectively confirm that the majority of children with ADHD will continue to express the disorder 4 years later. For a minority of children, ADHD was a transient disorder that remits early in development. In addition, we have shown that persistence of ADHD is predictable. Familiality, adversity, and psychiatric comorbidity may be clinically useful predictors of which children with ADHD are at risk for a persistent disorder.
引用
收藏
页码:343 / 351
页数:9
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