A new label-free and turn-on fluorescence probe for hydrogen peroxide and glucose detection based on DNA-silver nanoclusters

被引：14
作者：
Han, Hui-Xia [1 ]
Tian, Xue [1 ]
Kong, Xiang-Juan [1 ]
Yu, Ru-Qin [1 ]
Chu, Xia [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
来源：
ANALYTICAL METHODS | 2015年 / 7卷 / 19期
基金：
中国国家自然科学基金;
关键词：
GOLD NANOPARTICLES; BIOSENSOR; OXIDASE; ENHANCEMENT; ELECTRODE; LACTATE; ACID;
D O I：
10.1039/c5ay01546d
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
We have developed a reliable, sensitive, label-free and turn-on sensor for H2O2 and glucose based on the cleavage of ssDNA by cOH and the fluorescence enhancement effect when guanine-rich (G-rich) DNA sequences are in proximity to DNA-silver nanoclusters (DNA-Ag NCs). In addition, we have also proved that cOH is indeed produced in the sensing system by adding antioxidants.
引用
收藏
页码：7989 / 7994
页数：6
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