Inhibitors of glycosphingolipid biosynthesis

被引：29
作者：
Kolter, T
Sandhoff, K
机构：
[1] Inst. fur Org. Chem. und Biochem., Universität, 53121 Bonn
来源：
CHEMICAL SOCIETY REVIEWS | 1996年 / 25卷 / 06期
关键词：
D O I：
10.1039/cs9962500371
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Glycosphingolipids are membrane components of eukaryotic cells. They participate in various biological events and can regulate enzymes and receptors within the plasma membrane. Inhibitors of various stages of their biosynthesis have been isolated fr om natural sources or have been generated by design and chemical synthesis. They serve as valuable tools in the investigation of the physiological function of sphingolipids. Potential applications of these inhibitors are discussed in this article.
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页码：371 / &
页数：12
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