Macular Telangiectasia Type 2 Without Clinically Detectable Vasculopathy

被引：10

作者：

Gillies, Mark C. ^{[1
]}

Mehta, Hemal ^{[1
,2
]}

Bird, Alan C. ^{[2
]}

机构：

[1] Univ Sydney, Save Sight Inst, Macular Res Grp, Sydney, NSW 2006, Australia

[2] Moorfields Eye Hosp NHS Fdn Trust, Med Retina Serv, London, England

来源：

JAMA OPHTHALMOLOGY | 2015年 / 133卷 / 08期

关键词：

JUXTAFOVEOLAR RETINAL TELANGIECTASIS; PHOTORECEPTORS; CELLS;

D O I：

10.1001/jamaophthalmol.2015.1796

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

IMPORTANCE Macular telangiectasia type 2 is a bilateral disease with characteristic alterations of the macular capillary network and neural atrophy. Vascular and neurodegenerative hypotheses have been proposed to explain these clinical findings, but many questions regarding the pathogenesis remain. OBSERVATIONS We report the case of a 69-year-old woman with macular telangiectasia type 2 in whom multimodal fundus imaging identified neuronal features without clinically detectable vasculopathy. CONCLUSIONS AND RELEVANCE We hypothesize that parallel neuronal and vascular pathogenic pathways secondary to Muller cell dysfunction, the cause of which remains obscure, explain the clinical features of this case of macular telangiectasia type 2.

引用

页码：951 / 954

页数：4

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