Acute kidney injury due to tubular intraluminal monoclonal light chain crystals mimicking acute pyelonephritis

被引:8
作者
Haider, Mumnoon [1 ]
Salvatore, Steven P. [2 ]
Kaplan, Joshua [1 ]
Seshan, Surya V. [2 ]
机构
[1] Univ Med & Dent New Jersey, Dept Nephrol, Newark, NJ 07103 USA
[2] New York Presbyterian Hosp, Weill Cornell Med Coll, Dept Pathol & Lab Med, New York, NY USA
关键词
Acute kidney injury; light chain cast nephropathy; multiple myeloma; BENCE-JONES PROTEINS; MYELOMA KIDNEY; AMYLOIDOSIS; DISEASE; CELLS;
D O I
10.3109/0886022X.2013.844643
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Tubular intraluminal inflammatory cells may be seen in kidney biopsies of patients with pyelonephritis, cell-mediated transplant rejection, autoimmune tubulointerstitial nephritis, allergic reactions, or in association with monoclonal light chain casts. When casts in a native kidney are primarily composed of granulocytes, the cause is most commonly acute pyelonephritis due to an ascending bacterial urinary tract infection. We report a 57-year-old man with acute kidney injury and an intense intraluminal neutrophil response to monoclonal lambda light chain crystal containing casts.
引用
收藏
页码:300 / 305
页数:6
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