Treatment of Chronic Urticaria

被引：14

作者：

Asero, Riccardo ^{[1
]}

Tedeschi, Alberto ^{[2
]}

Cugno, Massimo ^{[3
]}

机构：

[1] Clin San Carlo, Ambulatorio Allergol Allergy Unit, I-20037 Milan, Italy

[2] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, UO Allergol Immunol Clin, Allergy & Clin Immunol Unit, I-20122 Milan, Italy

[3] Univ Milan, Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Pathophysiol & Transplantat, I-20122 Milan, Italy

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2014年 / 34卷 / 01期

关键词：

Chronic urticaria; Therapy; Antihistamines; Corticosteroids; Ciclosporin; Omalizumab; CHRONIC IDIOPATHIC URTICARIA; HISTAMINE-INDUCED WHEAL; CHRONIC AUTOIMMUNE URTICARIA; RESISTANT CHRONIC URTICARIA; LEUKOTRIENE RECEPTOR ANTAGONIST; CHRONIC UNREMITTING URTICARIA; STEROID-SPARING AGENT; LEVOCETIRIZINE; MG; SERUM SKIN-TEST; DOUBLE-BLIND;

D O I：

10.1016/j.iac.2013.09.013

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Second-generation antihistamines are unquestionably the first-line treatment for chronic urticaria and can be used at higher than licensed doses if normal doses fail to control the disease. A short course of oral corticosteroids should be considered for patients not responding to antihistamines before trying other immunosuppressive drugs. Ciclosporin is effective in most antihistamine-resistant patients who require long-term corticosteroid treatments to control their disease. Omalizumab is effective in most subsets of chronic urticaria sufferers who do not respond to other treatments but its high cost represents a limitation to its widespread use.

引用

页码：105 / +

页数：14

共 101 条

[1] Anti-CD20 or anti-IgE therapy for severe chronic autoimmune urticaria [J].

Arkwright, Peter D. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (02) :510-511

[2] Severe chronic urticaria is associated with elevated plasma levels of D-dimer [J].

Asero, R. ;

Tedeschi, A. ;

Riboldi, P. ;

Griffini, S. ;

Bonanni, E. ;

Cugno, M. .

ALLERGY, 2008, 63 (02) :176-180

[3] Oral cyclophosphamide in a case of cyclosporin and steroid-resistant chronic urticaria showing autoreactivity on autologous serum skin testing [J].

Asero, R .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2005, 30 (05) :582-583

[4] Plasma of patients with chronic urticaria shows signs of thrombin generation, and its intradermal injection causes wheal-and-flare reactions much more frequently than autologous serum [J].

Asero, R ;

Tedeschi, A ;

Riboldi, P ;

Cugno, M .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (05) :1113-1117

[5] Chronic unremitting urticaria: is the use of antihistamines above the licensed dose effective? A preliminary study of cetirizine at licensed and above-licensed doses [J].

Asero, R. .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2007, 32 (01) :34-38

[6]

Asero R, 2010, J INVEST ALLERG CLIN, V20, P386

[7] Leukotriene receptor antagonists in chronic urticaria [J].

Asero, R ;

Tedeschi, A ;

Lorini, M .

ALLERGY, 2001, 56 (05) :456-457

[8] Are IVIG for chronic unremitting urticaria effective? [J].

Asero, R .

ALLERGY, 2000, 55 (11) :1099-1101

[9] Activation of the tissue factor pathway of blood coagulation in patients with chronic urticaria [J].

Asero, Riccardo ;

Tedeschi, Alberto ;

Coppola, Raffaella ;

Griffini, Samantha ;

Paparella, Paolo ;

Riboldi, Piersandro ;

Marzano, Angelo V. ;

Fanoni, Daniele ;

Cugno, Massimo .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (03) :705-710

[10] Heparin and Tranexamic Acid Therapy May Be Effective in Treatment-Resistant Chronic Urticaria with Elevated D-Dimer: A Pilot Study [J].

Asero, Riccardo ;

Tedeschi, Alberto ;

Cugno, Massimo .

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2010, 152 (04) :384-389

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