Carbon-Dot-Based Nanosensors for the Detection of Intracellular Redox State

被引：87

作者：

Liu, Ye ^{[1
,2
]}

Tian, Ye ^{[1
,2
]}

Tian, Yefei ^{[1
,2
]}

Wang, Yajun ^{[3
]}

Yang, Wuli ^{[1
,2
]}

机构：

[1] Fudan Univ, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China

[2] Fudan Univ, Dept Macromol Sci, Shanghai 200433, Peoples R China

[3] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 44期

基金：

美国国家科学基金会;

关键词：

POLYMER CAPSULES; GLUTATHIONE; DISULFIDE; THIOLS; CELLS;

D O I：

10.1002/adma.201503662

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carbon-dot-based nanosensors are prepared through sequentially assembling a polymer/carbon dot multilayer shell on mesoporous silica nanoparticles with different crosslinking densities of disulfide bonds; they can be utilized to evaluate the gluthathione (GSH) concentration. In vitro cell assays demonstrate the feasibility of using such nano sensors in evaluating the intracellular redox state of different cells.

引用

页码：7156 / +

页数：6

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