Bridgehead enolates and bridgehead alkenes in a welwistatin model series

被引：22

作者：

Boissel, Valerie ^{[2
]}

Simpkins, Nigel S. ^{[2
]}

Bhalay, Gurdip ^{[1
]}

Blake, Alexander J. ^{[2
]}

Lewis, William ^{[2
]}

机构：

[1] Horsham Res Ctr, Novartis Inst Biomed Res, Global Discovery Chem, Horsham, W Sussex, England

[2] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 11期

关键词：

SKELETON; WELWITINDOLINONES; CLUSIANONE; EFFICIENT;

D O I：

10.1039/b820674k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bridgehead metallation is possible in a ketone having the welwistatin skeleton, and this facilitates installation of the isothiocyanate function present in the natural product, and also enables synthesis of remarkable bridgehead alkenes.

引用

页码：1398 / 1400

页数：3

共 23 条

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