Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors

被引：0
作者：
Reddy, G. Jagath
Rao, K. Srinivasa
机构：
[1] Dr Jagath Reddys Heterocycl, R&D Labs, Hyderabad 500037, Andhra Pradesh, India
[2] Jawaharlal Nehru Technol Univ, Oil Technol Res Inst, Anantapur 515001, Andhra Pradesh, India
[3] Univ Hyderabad, Sch Life Sci, Hyderabad 500046, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2006年 / 45卷 / 09期
关键词：
benzoxazin; nu-bromobenzoxazinyl butanoate; thiazolylbenzoxazinyl acetates; triazolothiadiazinyl benzoxazinyl acetate; COX-2; inhibitors;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of methyl 5-[2-arylamino-4-(3-oxo-[1,4]beilzoxazin-6-yl)thiazoleacetates 5a-h and 7H-[3-aryl-6-(3-oxo-[1,4]-benzoxazin-6-yl)-s-triazolo[3,4-b] [ 1,3,4] thiadiazin-7-yl] acetates 6a-e have been synthesized and tested for their COX-2 inhibitor activity.
引用
收藏
页码：2143 / 2146
页数：4
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