Evolving health care through personal genomics

被引：77

作者：

Rehm, Heidi L. ^{[1
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机构：

[1] Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA

[2] Harvard Med Sch, Boston, MA 02115 USA

[3] Partners Healthcare Personalized Med, Mol Med Lab, Cambridge, MA 02139 USA

[4] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA

来源：

NATURE REVIEWS GENETICS | 2017年 / 18卷 / 04期

基金：

美国国家卫生研究院;

关键词：

LUNG-CANCER; ADJUVANT CHEMOTHERAPY; DIAGNOSTIC ODYSSEY; GENETIC-VARIATION; MUTATIONS; SEQUENCE; CARDIOMYOPATHY; LABORATORIES; TRASTUZUMAB; ASSOCIATION;

D O I：

10.1038/nrg.2016.162

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

With the rapid evolution of next-generation DNA sequencing technologies, the cost of sequencing a human genome has plummeted, and genomics has started to pervade health care across all stages of life-from preconception to adult medicine. Challenges to fully embracing genomics in a clinical setting remain, but some approaches are starting to overcome these barriers, such as community-driven data sharing to improve the accuracy and efficiency of applying genomics to patient care. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.

引用

页码：259 / 267

页数：9

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