A specific structural interaction of Alzheimer's peptide A beta(1-42) with alpha(1)-antichymotrypsin

被引:40
|
作者
Janciauskiene, S
Eriksson, S
Wright, HT
机构
[1] VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT BIOCHEM & MOL BIOPHYS,RICHMOND,VA 23298
[2] LUND UNIV,MALMO GEN HOSP,DEPT MED,S-20502 MALMO,SWEDEN
来源
NATURE STRUCTURAL BIOLOGY | 1996年 / 3卷 / 08期
关键词
D O I
10.1038/nsb0896-668
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
alpha(1)-antichymotrypsin and Alzheimer's A beta(1-42) peptide appear to form a complex whose inferred structure suggests possible mechanisms for stimulation of Alzheimer's amyloid fibril formation.
引用
收藏
页码:668 / 671
页数:4
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