A simple and efficient one step synthesis of benzoxazoles and benzimidazoles from carboxylic acids

被引：155

作者：

Wang, Ying ^{[1
]}

Sarris, Kathy ^{[1
]}

Sauer, Daryl R. ^{[1
]}

Djuric, Stevan W. ^{[1
]}

机构：

[1] Abbott Labs, Global Pharmaceut Res & Dev, Med Chem Technol, High Throughput Organ Synth Grp, Abbott Pk, IL 60064 USA

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 28期

关键词：

D O I：

10.1016/j.tetlet.2006.05.052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzoxazoles or benzimidazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids with 2-aminophenols or 1,2-phenylenediamines in one simple step, respectively. The use of commercially available PS-PPh3 resin combined with microwave heating delivered a variety of benzoxazoles and benzimidazoles in high yields and purities. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4823 / 4826

页数：4

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