From Acetate to Bio-Based Products: Underexploited Potential for Industrial Biotechnology

被引：116

作者：

Kiefer, Dirk ^{[1
]}

Merkel, Manuel ^{[1
]}

Lilge, Lars ^{[1
]}

Henkel, Marius ^{[1
]}

Hausmann, Rudolf ^{[1
]}

机构：

[1] Univ Hohenheim, Inst Food Sci & Biotechnol, Dept Bioproc Engn, Fruwirthstr 12, D-70599 Stuttgart, Germany

来源：

TRENDS IN BIOTECHNOLOGY | 2021年 / 39卷 / 04期

关键词：

ACETIC-ACID RESISTANCE; ESCHERICHIA-COLI; LIPID PRODUCTION; MICROBIAL ELECTROSYNTHESIS; GAS FERMENTATION; LIGNOCELLULOSIC BIOMASS; ORGANIC-ACIDS; FATTY-ACIDS; CONVERSION; IMPROVES;

D O I：

10.1016/j.tibtech.2020.09.004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Currently, most biotechnological products are based on microbial conversion of carbohydrate substrates that are predominantly generated from sugar- or starch-containing plants. However, direct competitive uses of these feedstocks in the food and feed industry represent a dilemma, so using alternative carbon sources has become increasingly important in industrial biotechnology. A promising alternative carbon source that may be generated in substantial amounts from lignocellulosic biomass and C1 gases is acetate. This review discusses the underexploited potential of acetate to become a next-generation platform substrate in future industrial biotechnology and summarizes alternative sources and routes for acetate production. Furthermore, biotechnological aspects of microbial acetate utilization and the state of the art of biotechnological acetate conversion into value-added bioproducts are highlighted.

引用

页码：397 / 411

页数：15

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