Measuring Response with FDG-PET: Methodological Aspects

被引:47
作者
Allen-Auerbach, Martin [1 ]
Weber, Wolfgang A. [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Sch Med, Ahmanson Biol Imaging Ctr,Dept Mol & Med Pharmaco, Los Angeles, CA 90095 USA
关键词
Fluorodeoxyglucose; Positron emission tomography; Chemotherapy; Radiotherapy; Response; POSITRON-EMISSION-TOMOGRAPHY; STANDARDIZED UPTAKE VALUES; CELL LUNG-CANCER; METASTATIC BREAST-CANCER; EARLY METABOLIC-RESPONSE; PATHOLOGICAL RESPONSE; F-18; FLUORODEOXYGLUCOSE; ATTENUATION CORRECTION; PREOPERATIVE CHEMOTHERAPY; ESOPHAGOGASTRIC JUNCTION;
D O I
10.1634/theoncologist.2008-0119
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The use of fluorodeoxyglucose positron emission tomography (FDG-PET) for the evaluation of tumor response to chemotherapy and radiation therapy has been studied in a number of malignancies. By imaging tumor metabolism and therapy-related changes, FDG-PET has demonstrated advantages over anatomical imaging in the assessment of treatment response. More recent investigations have indicated that FDG-PET can predict tumor response early during the course of therapy, potentially allowing for early treatment adjustments. The aim of this review is to provide oncologists with a basic knowledge of the practical aspects of PET quantification for treatment. The Oncologist 2009; 14: 369-377
引用
收藏
页码:369 / 377
页数:9
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