Measuring solubility of ionisable compounds by a novel pH-metric approach: CheqSol (Chasing Equilibrium Solubility)

被引：0

作者：

Mole, Jon ^{[1
]}

Cimpan, Gabriela ^{[1
]}

机构：

[1] Karl Box Sinius Analyt Instruments Ltd, Forest Row RH18 5DW, England

来源：

ACTA PHARMACOLOGICA SINICA | 2006年 / 27卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：220 / 221

页数：2

共 13 条

[1] Solubility measurement of polymorphic compounds via the pH-metric titration technique
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[2] PH-METRIC DETERMINATION OF SOLUBILITY AND DISTRIBUTION RATIOS OF SOME ORGANIC COMPOUNDS IN EXTRACTION SYSTEMS
CHARYKOV, AK
TALNIKOV.TV
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[3] pH-metric solubility. 3. Dissolution titration template method for solubility determination
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Berger, CM
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2001, 14 (04) : 281 - 291
[4] Chasing equilibrium: Measuring the intrinsic solubility of weak acids and bases
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Box, K
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[5] pH-metric solubility. 2: Correlation between the acid-base titration and the saturation shake-flask solubility-pH methods
Avdeef, A
Berger, CM
Brownell, C
PHARMACEUTICAL RESEARCH, 2000, 17 (01) : 85 - 89
[6] pH-Metric Solubility. 2: Correlation Between the Acid-Base Titration and the Saturation Shake-Flask Solubility-pH Methods
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Pharmaceutical Research, 2000, 17 : 85 - 89
[7] Relationship between pKa, lipophilicity and solubility a novel approach for measuring ionizable compounds
Box, Karl
Cimpan, Gabriela
ACTA PHARMACOLOGICA SINICA, 2006, 27 : 220 - 220
[8] PH-METRIC TITRATION TECHNIQUE FOR STUDY OF METAL-COMPLEXES IN SOLUTION - NOVEL-APPROACH FOR CALCULATION OF EQUILIBRIUM-CONSTANTS
NAYAN, R
DEY, AK
JOURNAL OF INORGANIC & NUCLEAR CHEMISTRY, 1978, 40 (02): : 289 - 293
[9] Automated approach to couple solubility with final pH and crystallinity for pharmaceutical discovery compounds
Seadeek, Christopher
Ando, Howard
Bhattachar, Shobha N.
Heimbach, Tycho
Sonnenberg, Jason L.
Blackburn, Anthony C.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 43 (05) : 1660 - 1666
[10] A new approach for the thermodynamic modeling of the solubility of amino acids and β-lactam compounds as a function of pH
Mercier Franco, Luis Fernando
Mattedi, Silvana
Pessoa Filho, Pedro de Alcantara
FLUID PHASE EQUILIBRIA, 2013, 354 : 38 - 46

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