Bioactivities of nano-scale magnesium oxide prepared using aqueous extract of Moringa Oleifera leaves as green agent

被引：18

作者：

Amrulloh, Hanif ^{[1
]}

Fatiqin, Awalul ^{[2
]}

Simanjuntak, Wasinton ^{[3
]}

Afriyani, Hapin ^{[3
]}

Annissa, Annissa ^{[4
]}

机构：

[1] Inst Islamic Studies Maarif NU IAIMNU Metro Lampu, Fac Tarbiya, Dept Math Educ, Lampung, Indonesia

[2] Islamic State Univ Raden Fatah Palembang, Fac Sci & Technol, Dept Biol, Palembang, Indonesia

[3] Lampung Univ, Fac Math & Nat Sci, Dept Chem, Bandar Lampung, Indonesia

[4] Faletehan Univ, Hlth Fac, Dept Publ Hlth, Banten, Indonesia

来源：

ADVANCES IN NATURAL SCIENCES-NANOSCIENCE AND NANOTECHNOLOGY | 2021年 / 12卷 / 01期

关键词：

bioactivities; M; oleifera; nano-size MgO; antifungal; candidiasis;

D O I：

10.1088/2043-6254/abde39

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

In this research, nano-size MgO (NS-MgO) was prepared from MgCl2 solution using aqueous extract of Moringa oleifera leaves (AEMOL) as green agent. Preparation procedure involved mixing of MgCl2.6H(2)O solution and the AEMOL, followed by dropwise addition of NaOH solution. The formation of NS-MgO in this synthesis was confirmed using UV-Vis absorption. The spherical crystal structure of NS-MgO was confirmed by XRD analysis. The average particle size of the synthesised NS-MgO was found between 40-70 nm using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images and particle size analyser (PSA) results. Based on the maximum inhibition concentration (MIC) it was found that the NS-MgO has good antibacterial activity against S. aureus, E. faecalis, E. coli, and S. dysenteriae bacteria (MIC values: 250-500 mu g ml(-1)), and much stronger antifungal activity against A. flavus, A. niger, and C. albican (MIC values: 62.5-125 mu g ml(-1)). These findings suggest prospective potential of NS-MgO synthesised as therapeutic candidate for the treatment of candidiasis.

引用

页数：8