Opto-acousto-fluidic microscopy for three-dimensional label-free detection of droplets and cells in microchannels

被引：33
|
作者：
Song, Chaolong [1 ]
Jin, Tian [2 ,3 ]
Yan, Ruopeng [1 ]
Qi, Weizhi [2 ,3 ]
Huang, Tianye [1 ]
Ding, Huafeng [1 ]
Tan, Say Hwa [4 ]
Nam-Trung Nguyen [4 ]
Xi, Lei [2 ,3 ]
机构：
[1] China Univ Geosci Wuhan, Sch Mech Engn & Elect Informat, Wuhan, Hubei, Peoples R China
[2] Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen, Peoples R China
[3] Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu, Sichuan, Peoples R China
[4] Griffith Univ, Queensland Micro & Nanotechnol Ctr, 170 Kessels Rd, Brisbane, Qld 4111, Australia
来源：
LAB ON A CHIP | 2018年 / 18卷 / 09期
基金：
中国国家自然科学基金;
关键词：
MICROFLUIDICS; MICRODROPLETS; SPECTROSCOPY; PICOLITER; BIOLOGY; CHIP;
D O I：
10.1039/c8lc00106e
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
This paper reports a novel method, opto-acousto-fluidic microscopy, for label-free detection of droplets and cells in microfluidic networks. Leveraging the optoacoustic effect, the microscopic system possesses capabilities of visualizing flowing droplets, analyzing droplet contents, and detecting cell populations encapsulated in droplets via the sensing of acoustic waves induced by the intrinsic light-absorbance of matter.
引用
收藏
页码：1292 / 1297
页数：6
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