The role of dendritic cells in the innate immune system

被引:87
作者
Clark, GJ [1 ]
Angel, N [1 ]
Kato, M [1 ]
López, JA [1 ]
MacDonald, K [1 ]
Vuckovic, S [1 ]
Hart, DNJ [1 ]
机构
[1] Mater Misericordiae Univ Hosp, Mater Med Res Inst, Brisbane, Qld 4101, Australia
关键词
dendritic cell; antigen-presenting cell; innate immunity;
D O I
10.1016/S1286-4579(00)00302-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dendritic cells (DCs) are bone-marrow-derived leucocytes that are specialised antigen presenting cells capable of stimulating a primary T-lymphocyte response to specific antigen. In this chapter we discuss the role DCs play in the innate response acting as a critical link with the adaptive response and the influence of the innate response on dendritic cells. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:257 / 272
页数:16
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