Ca2+ bridges the C2 membrane-binding domain of protein kinase Cα directly to phosphatidylserine.

被引:0
|
作者
Gómez-Fernández, JC
Verdaguer, N
Corbalan-Garcia, S
Ochoa, W
Fita, I
机构
[1] Univ Murcia, Fac Vet, E-30080 Murcia, Spain
[2] CSIC, IBMB, Barcelona, Spain
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
85Plat
引用
收藏
页码:15A / 15A
页数:1
相关论文
共 50 条
  • [1] Ca2+ bridges the C2 membrane-binding domain of protein kinase Cα directly to phosphatidylserine
    Verdaguer, N
    Corbalan-Garcia, S
    Ochoa, WF
    Fita, I
    Gómez-Fernández, JC
    EMBO JOURNAL, 1999, 18 (22): : 6329 - 6338
  • [2] Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Cα to the plasma membrane
    Bolsover, SR
    Gomez-Fernandez, JC
    Corbalan-Garcia, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (12) : 10282 - 10290
  • [3] Dynamic Response of the C2 Domain of Protein Kinase Cα to Ca2+ Binding
    Morales, Krystal A.
    Yang, Yuan
    Cole, Taylor R.
    Igumenova, Tatyana I.
    BIOPHYSICAL JOURNAL, 2016, 111 (08) : 1655 - 1667
  • [4] Structure of the protein kinase Cβ phospholipid-binding C2 domain complexed with Ca2+
    Sutton, RB
    Sprang, SR
    STRUCTURE, 1998, 6 (11) : 1395 - 1405
  • [5] Mutagenesis of the C2 domain of protein kinase C-α -: Differential roles of Ca2+ ligands and membrane binding residues
    Medkova, M
    Cho, WW
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (28) : 17544 - 17552
  • [6] The C2 domain of protein kinase Cα is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane
    Conesa-Zamora, P
    Gómez-Fernández, JC
    Corbalán-García, S
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2000, 1487 (2-3): : 246 - 254
  • [7] Membrane-binding properties of the Factor VIII C2 domain
    Novakovic, Valerie A.
    Cullinan, David B.
    Wakabayashi, Hironao
    Fay, Philip J.
    Baleja, James D.
    Gilbert, Gary E.
    BIOCHEMICAL JOURNAL, 2011, 435 : 187 - 196
  • [8] INVOLVEMENT OF CA2+ IN THE COOPERATIVE BINDING OF PROTEIN-KINASE-C TO PHOSPHATIDYLSERINE
    NEWTON, AC
    UPHOFF, KW
    KERANEN, LM
    BIOPHYSICAL JOURNAL, 1994, 66 (02) : A344 - A344
  • [9] Structure of the C2 domain from novel protein kinase Cε.: A membrane binding model for Ca 2+-independent C2 domains
    Ochoa, WF
    Garcia-Garcia, J
    Corbalan-Garcia, IFS
    Verdaguer, N
    Gomez-Fernandez, JC
    JOURNAL OF MOLECULAR BIOLOGY, 2001, 311 (04) : 837 - 849
  • [10] Membrane binding kinetics of protein kinase C βII mediated by the C2 domain
    Nalefski, EA
    Newton, AC
    BIOCHEMISTRY, 2001, 40 (44) : 13216 - 13229