Esophageal Candidiasis as the Initial Manifestation of Acute Myeloid Leukemia

被引：1

作者：

Komeno, Yukiko ^{[1
]}

Uryu, Hideki ^{[1
]}

Iwata, Yuko ^{[1
]}

Hatada, Yasumasa ^{[2
]}

Sakamoto, Jumpei ^{[3
]}

Iihara, Kuniko ^{[4
]}

Ryu, Tomiko ^{[1
]}

机构：

[1] Tokyo Yamate Med Ctr, Dept Hematol, Japan Community Healthcare Org, Tokyo, Japan

[2] Tokyo Yamate Med Ctr, Dept Gastroenterol, Japan Community Healthcare Org, Tokyo, Japan

[3] Tokyo Yamate Med Ctr, Dept Ophthalmol, Japan Community Healthcare Org, Tokyo, Japan

[4] Tokyo Yamate Med Ctr, Dept Pathol, Japan Community Healthcare Org, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 23期

关键词：

Candida; esophageal candidiasis; leukemia; neutropenia; gastroendoscopy; INFECTIOUS-DISEASES SOCIETY; UPDATE; INNATE;

D O I：

10.2169/internalmedicine.54.4613

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 47-year-old woman presented with persistent dysphagia. A gastroendoscopy revealed massive esophageal candidiasis, and oral miconazole was prescribed. Three weeks later, she returned to our hospital without symptomatic improvement. She was febrile, and blood tests showed leukocytosis (137,150/mu L, blast 85%), anemia and thrombocytopenia. She was diagnosed with acute myeloid leukemia (AML). She received chemotherapy and antimicrobial agents. During the recovery from the nadir, bilateral ocular candidiasis was detected, suggesting the presence of preceding candidemia. Thus, esophageal candidiasis can be an initial manifestation of AML. Thorough examination to detect systemic candidiasis is strongly recommended when neutropenic patients exhibit local candidiasis prior to chemotherapy.

引用

页码：3087 / 3092

页数：6

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