Biomechanical analysis of four- versus six-screw constructs for short-segment pedicle screw and rod instrumentation of unstable thoracolumbar fractures

BACKGROUND CONTEXT: Conventionally, short-segment fusion involves instrumentation of one healthy vertebra above and below the injured vertebra, skipping the injured level. This short-segment construct places less surgical burden on the patient compared with long-segment constructs, but is less stable biomechanically, and thus has resulted in clinical failures. The addition of two screws placed in the fractured vertebral body represents an attempt to improve the construct stiffness without sacrificing the benefits of short-segment fusion. PURPOSE: To determine the biomechanical differences between four-and six-screw short-segment constructs for the operative management of an unstable L1 fracture. STUDY DESIGN: Biomechanical study of instrumentation in vertebral body cadaveric models simulating an L1 axial load injury pattern. METHODS: Thirteen intact spinal segments from T12 to L2 were prepared from fresh-frozen cadaver spines. An axial load fracture of at least 50% vertebral body height was produced at L1 and then instrumented with pedicle screws. Specimens were evaluated in terms of construct stiffness, motion, and rod strain. Two conditions were tested: a four-screw construct with no screws at the L1 fractured body (4S) and a six-screw construct with screws at all levels (6S). The two groups were compared statistically by paired Student t test. RESULTS: The mean stiffness in flexion-extension was increased 31% (p < .03) with the addition of the two pedicle screws in L1. Relative motion in terms of vertical and axial rotations was not significantly different between the two groups. The L1-L2 rod strain was significantly increased in the six-screw construct compared with the four-screw construct (p < .001). CONCLUSIONS: In a cadaveric L1 axial load fracture model, a six-screw construct with screws in the fractured level is more rigid than a four-screw construct that skips the injured vertebral body. (C) 2014 Elsevier Inc. All rights reserved.