Nutritional Controls of Food Reward

被引:15
作者
Fernandes, Maria F. [1 ,2 ,4 ]
Sharma, Sandeep [1 ,2 ,3 ]
Hryhorczuk, Cecile [1 ,2 ,4 ]
Auguste, Stephanie [1 ,2 ,3 ]
Fulton, Stephanie [1 ,2 ,3 ]
机构
[1] Univ Montreal, CRCHUM, Montreal, PQ, Canada
[2] Univ Montreal, Montreal Diabet Res Ctr, Montreal, PQ, Canada
[3] Univ Montreal, Fac Med, Dept Nutr, Montreal, PQ H3C 3J7, Canada
[4] Univ Montreal, Fac Med, Dept Physiol, Montreal, PQ H3C 3J7, Canada
关键词
dopamine; feeding; ghrelin; hedonic; insulin; leptin; nucleus accumbens; obesity; reinforcement; striatum; VENTRAL TEGMENTAL AREA; HIGH-FAT DIET; MELANIN-CONCENTRATING HORMONE; MESOLIMBIC DOPAMINE SYSTEM; BRAIN-STIMULATION REWARD; NUCLEUS-ACCUMBENS SHELL; PALATABLE HIGH-FAT; PROGRESSIVE-RATIO; NEUROPEPTIDE-Y; LEPTIN RECEPTOR;
D O I
10.1016/j.jcjd.2013.04.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The propensity to select and consume palatable nutrients is strongly influenced by the rewarding effects of food. Neural processes integrating reward, emotional states and decision-making can supersede satiety signals to promote excessive caloric intake and weight gain. While nutritional habits are influenced by reward-based neural mechanisms, nutrition and its impact on energy metabolism, in turn, plays an important role in the control of food reward. Feeding modulates the release of metabolic hormones that have an important influence on central controls of appetite. Nutrients themselves are also an essential source of energy fuel, while serving as key metabolites and acting as signalling molecules in the neural pathways that control feeding and food reward. Along these lines, this review discusses the impact of nutritionally regulated hormones and select macronutrients on the behavioural and neural processes underlying the rewarding effects of food. (C) 2013 Canadian Diabetes Association
引用
收藏
页码:260 / 268
页数:9
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