Investigation of Proline Amides and Pyridinium Salts as Catalyst for Direct Aldol Reactions in Water

被引：0

作者：

Ozkan, Asli ^{[1
]}

Mavis, Murat Emrah ^{[1
]}

Aydogan, Feray ^{[1
]}

Yolacan, Cigdem ^{[1
]}

机构：

[1] Yildiz Tekn Univ, Dept Chem, TR-34010 Istanbul, Turkey

来源：

JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN | 2014年 / 36卷 / 02期

关键词：

Aldol reactions; Green chemistry; Homogeneous catalysis; Phase-transfer catalysis; Proline amides; Pyridinium salts; PHASE-TRANSFER CATALYSIS; ASYMMETRIC ORGANOCATALYSIS; INHIBITORS; ALDEHYDES; EFFICIENT; LIGANDS; KETONES; MEDIA;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The catalytic potential of chiral proline amides and pyridinium salts in the aldol condensation in water was investigated. The aldol reactions of acetone with various aromatic aldehydes were carried out in water by using proline amide derivatives and pyridinium salts derived from chiral pyridine derivatives for the first time. The products were obtained in good yields within short reaction times.

引用

页码：326 / 331

页数：6

共 44 条

[11] Synthesis and utilization of 13C and 15N backbone-labeled proline:: NMR study of synthesized oxytocin with backbone-labeled C-terminal tripeptide amide [J].

Budesínsky, M ;

Ragnarsson, U ;

Lankiewicz, L ;

Grehn, L ;

Slaninová, J ;

Hlavácek, J .

AMINO ACIDS, 2005, 29 (02) :151-160

[12] Proline-based dipeptides with two amide units as organocatalyst for the asymmetric aldol reaction of cyclohexanone with aldehydes [J].

Chen, Fubin ;

Huang, Shi ;

Zhang, Hui ;

Liu, Fengying ;

Peng, Yungui .

TETRAHEDRON, 2008, 64 (40) :9585-9591

[13] Electron deficiency of aldehydes controls the pyrrolidine catalyzed direct cross-aldol reaction of aromatic/heterocyclic aldehydes and ketones in water [J].

Chimni, SS ;

Mahajan, D .

TETRAHEDRON, 2005, 61 (21) :5019-5025

[14] Small organic molecule catalyzed enantioselective direct aldol reaction in water [J].

Chimni, Swapandeep Singh ;

Mahajan, Dinesh .

TETRAHEDRON-ASYMMETRY, 2006, 17 (14) :2108-2119

[15] Enantioselective direct aldol reaction:: the blossoming of modern organocatalysis [J].

Guillena, Gabriela ;

Najera, Carmen ;

Ramon, Diego J. .

TETRAHEDRON-ASYMMETRY, 2007, 18 (19) :2249-2293

[16] l-Valine Dipeptide Organocatalysts with Two Amide Units for the Direct Asymmetric Aldol Reaction in Brine [J].

Huang, Wenbo ;

Tian, Hua ;

Xu, Hao ;

Zheng, Liangyu ;

Liu, Qingwen ;

Zhang, Suoqin .

CATALYSIS LETTERS, 2011, 141 (06) :872-876

[17] Studies on the enzymatic kinetic resolution of β-hydroxy ketones [J].

Joly, S ;

Nair, MS .

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2003, 22 (3-4) :151-160

[18]

Jones R.A., 2001, QUATERNARY AMMONIUM

[19] L-t-Leucine-Catalyzed Direct Asymmetric Aldol Reaction of Cyclic Ketones [J].

Kanemitsu, Takuya ;

Umehara, Atsushi ;

Miyazaki, Michiko ;

Nagata, Kazuhiro ;

Itoh, Takashi .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 2011 (05) :993-997

[20] Dipeptide-catalyzed direct asymmetric aldol reactions in the presence of water [J].

Lei, Meng ;

Shi, Lanxiang ;

Li, Gong ;

Chen, Shilv ;

Fang, Weihai ;

Ge, Zemei ;

Cheng, Tieming ;

Li, Runtao .

TETRAHEDRON, 2007, 63 (33) :7892-7898

← 1 2 3 4 5 →