Three new diphenyl ethers from the lichen Parmotrema praesorediosum (Nyl.) Hale (Parmeliaceae)

被引：3

作者：

Huynh, Bui Linh Chi ^{[1
]}

Bui, Van Muoi ^{[2
]}

Nguyen, Kim Phi Phung ^{[2
]}

Pham, Nguyen Kim Tuyen ^{[3
]}

Nguyen, Tan Phat ^{[4
,5
]}

机构：

[1] Dong Nai Univ, Dept Sci, Bien Hoa City, Vietnam

[2] Natl Univ HCM City, Univ Sci, Dept Chem, Ho Chi Minh City, Vietnam

[3] Sai Gon Univ, Fac Environm Sci, Ho Chi Minh City, Vietnam

[4] Grad Univ Sci & Technol, Acad Sci & Technol, Fac Chem, Hanoi, Vietnam

[5] Vietnam Acad Sci & Technol, Inst Chem Technol, Bioact Cpds Lab, Ho Chi Minh City, Vietnam

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 08期

关键词：

Parmotrema praesorediosum; Parmeliaceae; praesorether; diphenyl ether; cytotoxicity; CHEMOPREVENTION; LEAVES;

D O I：

10.1080/14786419.2020.1837818

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Three new diphenyl ethers, named praesorethers E, F and G (1, 2 and 3), were isolated from the lichen Parmotrema praesorediosum. Their chemical structures were elucidated on the basis of extensively spectroscopic analysis including HR-ESI-MS and NMR as well as comparison with previously published data. These compounds were evaluated for the cytotoxicity against three human cancer cell lines (HeLa, NCI-H460 and MCF-7) using SRB assay. As results, 1 and 2 exhibited weak cytotoxic activity against three tested cancer cell lines with the inhibitive percentage of 64-79.9% at the concentration of 100 mu g/mL while 3 was inactive.

引用

页码：1934 / 1940

页数：7

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