FlyBase at 25: looking to the future

被引：396

作者：

Gramates, L. Sian ^{[1
]}

Marygold, Steven J. ^{[2
]}

dos Santos, Gilberto ^{[1
]}

Urbano, Jose-Maria ^{[2
]}

Antonazzo, Giulia ^{[2
]}

Matthews, Beverley B. ^{[1
]}

Rey, Alix J. ^{[2
]}

Tabone, Christopher J. ^{[1
]}

Crosby, Madeline A. ^{[1
]}

Emmert, David B. ^{[1
]}

Falls, Kathleen ^{[1
]}

Goodman, Joshua L. ^{[3
]}

Hu, Yanhui ^{[4
]}

Ponting, Laura ^{[2
,5
]}

Schroeder, Andrew J. ^{[1
,6
]}

Strelets, Victor B. ^{[3
]}

Thurmond, Jim ^{[3
]}

Zhou, Pinglei ^{[1
]}

机构：

[1] Harvard Univ, Biol Labs, 16 Divinity Ave, Cambridge, MA 02138 USA

[2] Univ Cambridge, Dept Physiol Dev & Neurosci, Downing St, Cambridge CB2 3DY, England

[3] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA

[4] Harvard Med Sch, Dept Genet, 77 Ave Louis Pasteur, Boston, MA 02115 USA

[5] Wellcome Trust Sanger Inst, Wellcome Genome Campus, Hinxton CB10 1SA, England

[6] Harvard Med Sch, Dept Biomed Informat, Boston, MA 02115 USA

来源：

NUCLEIC ACIDS RESEARCH | 2017年 / 45卷 / D1期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

PROTEIN FAMILIES DATABASE; CELL FATE; DROSOPHILA; RESOURCE; VERSATILE; SEQUENCE; CATALOG; UPDATE;

D O I：

10.1093/nar/gkw1016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since 1992, FlyBase (flybase.org) has been an essential online resource for the Drosophila research community. Concentrating on the most extensively studied species, Drosophila melanogaster, FlyBase includes information on genes (molecular and genetic), transgenic constructs, phenotypes, genetic and physical interactions, and reagents such as stocks and cDNAs. Access to data is provided through a number of tools, reports, and bulk-data downloads. Looking to the future, FlyBase is expanding its focus to serve a broader scientific community. In this update, we describe new features, datasets, reagent collections, and data presentations that address this goal, including enhanced orthology data, Human Disease Model Reports, protein domain search and visualization, concise gene summaries, a portal for external resources, video tutorials and the FlyBase Community Advisory Group.

引用

页码：D663 / D671

页数：9

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