Intracranial atherosclerosis

被引：366
作者：
Qureshi, Adnan I. [1 ,2 ]
Caplan, Louis R. [3 ]
机构：
[1] Zeenat Qureshi Stroke Inst, St Cloud, MN 56303 USA
[2] CentraCare Hlth, St Cloud, MN USA
[3] Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA 02215 USA
来源：
LANCET | 2014年 / 383卷 / 9921期
基金：
美国国家卫生研究院;
关键词：
TRANSIENT ISCHEMIC ATTACK; CEREBRAL-ARTERY STENOSIS; HEALTH-CARE PROFESSIONALS; RISK-FACTORS; STROKE PATIENTS; RECURRENT STROKE; CT-ANGIOGRAPHY; CEREBROVASCULAR-DISEASE; TRANSCRANIAL DOPPLER; SECONDARY PREVENTION;
D O I：
10.1016/S0140-6736(13)61088-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Atherosclerotic disease often involves the intracranial arteries including those encased by cranial bones and dura, and those located in the subarachnoid space. Age, hypertension, and diabetes mellitus are independent risk factors for intracranial atherosclerosis. Intracranial atherosclerosis can result in thromboembolism with or without hypoperfusion leading to transient or permanent cerebral ischaemic events. High rates of recurrent ischaemic stroke and other cardiovascular events mandate early diagnosis and treatment. Present treatment is based on a combination of antiplatelet drugs, optimisation of blood pressure and LDL cholesterol values, and intracranial angioplasty or stent placement, or both, in selected patients.
引用
收藏
页码：984 / 998
页数：15
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