A novel simple and efficient bromination protocol for activated arenes

被引:23
作者
Tsoukala, Anna [1 ]
Liguori, Lucia [2 ]
Occhipinti, Giovanni [1 ]
Bjorsvika, Hans-Rene [1 ]
机构
[1] Univ Bergen, Dept Chem, N-5007 Bergen, Norway
[2] Fluens Synth AS, N-5008 Bergen, Norway
关键词
Bromination; Oxidation; Redox; Chemoselectivity; Green chemistry; Electrophilic substitution; ALKYL PHENYL ETHERS; AROMATIC-COMPOUNDS; POTASSIUM-BROMIDE; METAL BROMIDES; MONOBROMINATION; HALOGENATION; MECHANISM; OXONE(R); SOLVENT; HALIDE;
D O I
10.1016/j.tetlet.2008.12.016
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient, high yielding, and environmentally benign bromination using an alkali metal bromide as the bromine source is disclosed. Investigation of the protocol revealed that the method operates for activated arenes producing the corresponding monobrominated products in good to excellent yields. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:831 / 833
页数:3
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