Mechanisms of anxiety - a reappraisal on GABAA receptor subunits and role of benzodiazepines

被引：0
作者：
Novais, C. [1 ]
Fernandes, H. [1 ]
Vieira-Coelho, M. [2 ]
机构：
[1] BIAL Portela & Ca SA, Dept Res & Dev, Coronado S Romao e S Mam, Portugal
[2] Ctr Hosp Univ Sao Joao, Psychiat, Porto, Portugal
来源：
EUROPEAN PSYCHIATRY | 2020年 / 63卷
关键词：
benzodiazepine; GABAA receptor; Anxiety;
D O I：
暂无
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
EPV0104
引用
收藏
页码：S300 / S300
页数：1
相关论文
共 50 条
[41]   THE INFLUENCE OF STRESS AT PUBERTY ON MOOD AND LEARNING: ROLE OF THE α4βδ GABAA RECEPTOR [J].
Smith, S. S. .
NEUROSCIENCE, 2013, 249 :192-213
[42]   Short- and long-term effects of juvenile stressor exposure on the expression of GABAA receptor subunits in rats [J].
Jacobson-Pick, Shlomit ;
Richter-Levin, Gal .
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, 2012, 15 (04) :416-424
[43]   Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans [J].
Bianchi, MT ;
Song, LY ;
Zhang, H ;
Macdonald, RL .
JOURNAL OF NEUROSCIENCE, 2002, 22 (13) :5321-5327
[44]   Mice lacking the long splice variant of the γ2 subunit of the GABAA receptor are more sensitive to benzodiazepines [J].
Quinlan, JJ ;
Firestone, LL ;
Homanics, GE .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2000, 66 (02) :371-374
[45]   3D-QSAR study of benzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [J].
Lu, AJ ;
Liu, B ;
Liu, HB ;
Zhou, JJ .
ACTA PHYSICO-CHIMICA SINICA, 2004, 20 (05) :488-493
[46]   Differential effects of GABAA receptor activation in the prelimbic and orbitofrontal cortices on anxiety [J].
Green, Trudy A. ;
Baracz, Sarah J. ;
Everett, Nick A. ;
Robinson, Katherine J. ;
Cornish, Jennifer L. .
PSYCHOPHARMACOLOGY, 2020, 237 (11) :3237-3247
[47]   SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms [J].
Griebel, G ;
Perrault, G ;
Simiand, J ;
Cohen, C ;
Granger, P ;
Depoortere, H ;
Françon, D ;
Avenet, P ;
Schoemaker, H ;
Evanno, Y ;
Sevrin, M ;
George, P ;
Scatton, B .
CNS DRUG REVIEWS, 2003, 9 (01) :3-20
[48]   Differential effects of GABAA receptor activation in the prelimbic and orbitofrontal cortices on anxiety [J].
Trudy A. Green ;
Sarah J. Baracz ;
Nick A. Everett ;
Katherine J. Robinson ;
Jennifer L. Cornish .
Psychopharmacology, 2020, 237 :3237-3247
[49]   Short-term exposure to a neuroactive steroid increases α4 GABAA receptor subunit levels in association with increased anxiety in the famale rat [J].
Gulinello, M ;
Gong, QH ;
Li, X ;
Smith, SS .
BRAIN RESEARCH, 2001, 910 (1-2) :55-66
[50]   Deduction of amino acid residues in the GABAA receptor α subunits photoaffinity labeled with the benzodiazepine flunitrazepam [J].
Smith, GB ;
Olsen, RW .
NEUROPHARMACOLOGY, 2000, 39 (01) :55-64
12345