Dynamic particle ordering in oscillatory inertial microfluidics

被引：30

作者：

Dietsche, Claudius ^{[1
,2
]}

Mutlu, Baris R. ^{[1
]}

Edd, Jon F. ^{[1
,3
]}

Koumoutsakos, Petros ^{[2
]}

Toner, Mehmet ^{[1
,4
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Boston, MA 02114 USA

[2] Swiss Fed Inst Technol, Computat Sci & Engn Lab, Clausiusstr 33, CH-8092 Zurich, Switzerland

[3] Harvard Med Sch, Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[4] Shriners Hosp Children, Boston, MA 02114 USA

来源：

MICROFLUIDICS AND NANOFLUIDICS | 2019年 / 23卷 / 06期

关键词：

Microfluidics; Oscillatory flow; Inertial focusing; Train of particles; Hydrodynamic self-assembly; SEPARATION; FLOW; CELLS;

D O I：

10.1007/s10404-019-2242-x

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Particles suspended in conduit flows at small and intermediate Reynolds numbers cluster on specific focal positions while also forming particle pairs and trains due to flow-mediated interactions. The recent introduction of oscillatory inertial microfluidics has enabled the creation of virtually infinite channels, allowing the manipulation of particles at extremely low particle Reynolds numbers (Re-p<<1). Here, we investigate experimentally the dynamics of formation, the robustness and the stability of particle pairs, and the precision of the inter-particle distance in an oscillatory flow field, in microchannels with a rectangular cross section. Our results indicate that the cross-sectional arrangement of the particles is fundamental in determining the characteristics of the resulting particle pair.

引用

页数：8

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