In vivo neurochemical monitoring by microdialysis and capillary separations

被引：88
作者：
Kennedy, RT
Watson, CJ
Haskins, WE
Powell, DH
Strecker, RE
机构：
[1] Univ Michigan, Dept Chem & Pharmacol, Ann Arbor, MI 48109 USA
[2] Harvard Med Sch, Brockton, MA 02301 USA
[3] VA Med Ctr, Brockton, MA 02301 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 05期
关键词：
D O I：
10.1016/S1367-5931(02)00373-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Microdialysis is valuable for studying the neurochemical changes underlying behavior. Recent advances include the application of the high-sensitivity methods of capillary electrophoresis and capillary liquid chromatography with mass spectrometry to dialysate analysis, These methods have improved temporal resolution, spatial resolution, multi-analyte capability and potential for compound discovery.
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收藏
页码：659 / 665
页数：7
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