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Cellular immune responses against viral pathogens in shrimp
被引:55
|作者:
Xu, Dandan
[1
]
Liu, Weifeng
[4
]
Alvarez, Angel
[5
]
Huang, Tianzhi
[2
,3
,5
]
机构:
[1] Zhejiang Univ, Inst Cell Biol, Hangzhou 310058, Zhejiang, Peoples R China
[2] Zhejiang Univ, Minist Educ, Key Lab Conservat Biol Endangered Wildlife, Hangzhou 310058, Zhejiang, Peoples R China
[3] Zhejiang Univ, Minist Agr, Key Lab Anim Virol, Hangzhou 310058, Zhejiang, Peoples R China
[4] Albert Einstein Coll Med, Bronx, NY 10461 USA
[5] Northwestern Univ, Feinberg Sch Med, Ken & Ruth Davee Dept Neurol, Chicago, IL 60611 USA
关键词:
Shrimp;
Phagocytosis;
Apoptosis;
RNAi;
SPOT-SYNDROME-VIRUS;
DOUBLE-STRANDED-RNA;
BLACK TIGER SHRIMP;
C-TYPE LECTIN;
PENAEUS-MONODON;
LITOPENAEUS-VANNAMEI;
ANTIVIRAL IMMUNITY;
INNATE IMMUNITY;
FUNCTIONAL-CHARACTERIZATION;
SILENCING PATHWAY;
D O I:
10.1016/j.dci.2014.08.004
中图分类号:
S9 [水产、渔业];
学科分类号:
0908 ;
摘要:
Shrimp is one of the most important commercial marine species worldwide; however, viral diseases threaten the healthy development of shrimp aquaculture. In order to develop efficient control strategies against viral diseases, researchers have begun focusing increasing attention to the molecular mechanism of shrimp innate immunity. Although knowledge of shrimp humoral immunity has grown significantly in recent years, very little information is available about the cell-mediated immune responses. Several cellular processes such as phagocytosis, apoptosis, and RNA interference critical in cellular immune response play a significant role in endogenous antiviral activity in shrimp. In this review, we summarize the emerging research and highlight key mediators of cellular immune response to viral pathogens. (C) 2014 Elsevier Ltd. All rights reserved.
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页码:287 / 297
页数:11
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