Model for tracing the path of microparticles in continuous flow microfluidic devices for 2D focusing via standing acoustic waves

被引:16
作者
Mathew, Bobby [1 ]
Alazzam, Anas [1 ]
El-Khasawneh, Bashar [1 ]
Maalouf, Maher [2 ]
Destgeer, Ghulam [3 ]
Sung, Hyung Jin [3 ]
机构
[1] Khalifa Univ, Dept Mech Engn, Coll Engn, Abu Dhabi, U Arab Emirates
[2] Khalifa Univ, Dept Ind & Syst Engn, Coll Engn, Abu Dhabi, U Arab Emirates
[3] Korea Adv Inst Sci & Technol, Dept Mech Engn, Daejeon, South Korea
关键词
Dynamic model; Focusing; Microparticles; Microchannel; Standing acoustic waves; CONTINUOUS SEPARATION; PARTICLES; RESONATORS; CHANNEL; MOTION;
D O I
10.1016/j.seppur.2015.08.026
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
An, experimentally validated, two-dimensional dynamic model for tracing the path of microparticles in a microfluidic layered transducer is developed. The model is based on Newton's 2nd law and considers forces due to inertia, gravity, buoyancy, virtual mass and acoustics; it is solved using finite difference method. Microparticles' trajectory consists of transient and steady state phases. All operating and geometric parameters are influential during the transient phase. The final levitation height is independent of the radius and initial vertical location of the microparticle as well as volumetric flow rate; however, dependent on the acoustic energy density and wavelength. There exists a threshold acoustic energy density for levitating microparticles from a specific initial vertical displacement; analytical equation for determining this acoustic energy density is provided. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:99 / 107
页数:9
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