One-pot multicomponent synthesis hexahydroquinoline derivatives in Triton X-100 aqueous micellar media

被引：13

作者：

Heravi, Mohammad Reza Poor ^{[1
]}

Mehranfar, Shadi ^{[1
]}

Shabani, Nemat ^{[1
]}

机构：

[1] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran

来源：

COMPTES RENDUS CHIMIE | 2014年 / 17卷 / 02期

关键词：

Multicomponent reactions (MCRs); One-pot reaction; Hexahydroquinolines; Triton X-100; Non-ionic surfactant; Dimedone; POLYHYDROQUINOLINE DERIVATIVES; EFFICIENT SYNTHESIS; HANTZSCH REACTION; CATALYZED FACILE; AMMONIUM-NITRATE; 1,4-DIHYDROPYRIDINES; ESTERS; ACID;

D O I：

10.1016/j.crci.2012.11.017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and efficient synthesis of hexahydroquinoline derivatives (5a-o) was reported via a four-component condensation reaction of aldehydes, dimedone, methyl aceto acetate and ammonium acetate in the presence of Triton X-100 in water at room temperature. The use of just 20 mol % of Triton X-100 in water solvent is sufficient. The FT-IR, F-19 NMR, H-1 NMR, C-13 NMR spectra and elemental analysis confirm the structure of the compounds. (c) 2012 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：141 / 145

页数：5

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